There are some reports on aldolase (Aldoa) activity in B chronic lymphocytic leukaemia and hyperaldolasaemia has been detected in patients with AML [28]; although literature screening failed to find a known direct involvement of Enolase 1 (Eno1) in AML, it is a tumour marker without recognised role in cancer [29]. This evidence concerns the gene ENO1 and acute myeloid leukemia.