Partly because of the more limited range of proteins analysed, the commonly deregulated proteins were fewer in number with just 3 being commonly deregulated in the three primary and in vivo passaged samples, Fkbp5, Tln1 and Tuba4a and just one, Fkbp5, commonly deregulated in all AML materials (cell lines, in vivo passaged MLP3 and primary AMLs). Here, TUBA4A is linked to acute myeloid leukemia.