ENO1 and B-cell chronic lymphocytic leukemia: There are some reports on aldolase (Aldoa) activity in B chronic lymphocytic leukaemia and hyperaldolasaemia has been detected in patients with AML [28]; although literature screening failed to find a known direct involvement of Enolase 1 (Eno1) in AML, it is a tumour marker without recognised role in cancer [29].