CASC8 and non-small cell lung carcinoma: We found that CASC8 rs10505477 polymorphism was statistically correlated with severe hematologic toxicity in NSCLC subgroup in dominant and additive models (adjusted OR = 0.59, 95%CI = 0.35–0.98, p = 0.04 in dominant model; adjusted OR = 0.62, 95%CI = 0.43–0.90, p = 0.01 in additive model, Table 10).