Presenting symptoms among 57 patients with germline GATA2 deficiency from the National Institutes of Health (NIH) cohort were described, including viral infections in 23%, disseminated non-tuberculosis mycobacterial infections in 28%, MDS/AML in 21%, lymphedema in 9%, and invasive fungal infections in 4% [19]. The gene discussed is GATA2; the disease is acute myeloid leukemia.