Mantle cell lymphoma (MCL) is a distinct subtype of malignant B-cell non Hodgkin lymphoma characterized by the t(11;14)(q13;q32) chromosomal translocation, resulting in constitutional overexpression of cyclin D1 and subsequent deregulation of the cyclin D/Rb protein pathway [1, 2]. Here, CCND1 is linked to mantle cell lymphoma.