Consistently with in vitro findings obtained in MCL cells overexpressing PLSCR1, no correlation was found between PLSCR1 expression and Ki-67 or cleaved caspase-3 in the MCL biopsies investigated, indicating that PLSCR1 per se does probably not play a role in regulating MCL cell proliferation or survival. This evidence concerns the gene CASP3 and mantle cell lymphoma.