TACC3 and colorectal carcinoma: To identify a new biomarker and potential treatment target for CRC, we analysed transcript expression microarray data from the Oncomine database (GSE20916; N = 40, T = 96) and identified a differentially expressed gene called TACC3 that was over-expressed in CRC samples compared with normal controls (P < 0.001) (Figure 1A).