Age, sex, insulin resistance, systemic hypertension, TG, ALT, AST, GGT, AST/ALT ratio, α2-macroglobulin, haptoglobin, apolipoprotein A1, total bilirubin, fasting blood glucose and fibrosis-4 were found to be associated with NASH and have been used in various diagnostic panels [23, 27, 28]. This evidence concerns the gene HP and metabolic dysfunction-associated steatohepatitis.