Since no data on the expression and functions of TRPML-2 channels in gliomas has been provided so far, the present work evaluated the expression of TRPML-2 channels in astrocytomas and glioblastomas compared to normal brain tissues (NB), astrocytes (NHA) and neural stem/progenitor cells (NS/PC). Here, MCOLN2 is linked to glioblastoma.