ALDH2 and anemia: Interestingly, a similar phenotype was described for double knockout Aldh2−/−/Fancd2−/− mice in a study demonstrating that the acetaldehyde-catabolizing enzyme aldehyde dehydrogenase 2 (Aldh2) is essential for embryonic viability of mice deficient in the Fanconi anemia complementation group D2 (Fancd2) DNA repair gene [1].