HP and non-small cell lung carcinoma: Park J et al. utilized stable isotope dilution-multiple reaction monitoring mass spectrometry to investigated the circulating concentration of haptoglobin subunits in 210 NSCLC patients, found serum levels of haptoglobin alpha and beta chains were obviously elevated in NSCLC compared with controls, could be a biomarker for the diagnosis of NSCLC, but lacking of prognostic data [6].