ITGB3 and acute myeloid leukemia: In FLT3 wild type AML patients, there was no difference of OS between two groups depends on the expression level of ITGB3 (Figure 1F), however, in patients who had normal cytogenetics with FLT3 mutation, the OS of patients with higher ITGB3 expression was significantly worse compared that of patients with lower ITGB3 (Figure 1G).