All 11 verified SNVs and rare SNPs detected by amplicon sequencing in the CDS of the RTKs EGFR, EPHA2, ERBB3, IGF1R, NTRK1 and NTRK2 were not described previously according to the cosmic database (http://cancer.sanger.ac.uk/cosmic) and they collectively affected 10 out of 75 primary MM cases (13%) of the current study. Here, IGF1R is linked to Miyoshi myopathy.