DPP4 and diabetes mellitus: A recent retrospective study on DDP-4 inhibitors prescribed to elderly diabetes patients (median age 70 years, range 60–92 years) found that median A1C improved from 8.3 to 7.4 % and DDP-4 inhibitors treated patients had a lower rate of documented hypoglycemia than the non-DPP-4 inhibitors treated group (3 vs. 8 %) [22].