TP53 and lymphoma: None of the Mps1f/fLck-Cre+ (n = 71) or Lck-Cre− animals (n = 63) succumbed to lymphoma within the first year (Fig. 3a, green and purple lines, respectively), while both the Mps1f/f; p53f/f; Lck-Cre+ (n = 31) and Mps1f/f; p53+/f; Lck-Cre+ (n = 58) developed T-ALLs with median latencies of 3.4 and 4.0 months, respectively (Fig. 3a, blue and red lines, respectively), identical as in our previous cohorts [15].