Alterations in pro- and anti-inflammatory cytokines and growth factors such as IL-6, IL-10, GM-CSF, G-CSF, IL-2, IL-4, IL-8, IL12, IL-15, IL-17, IL-18, basic FGF, VEGF, and IFN-gamma were observed in CSF of ALS patients [9–12]. Here, IL18 is linked to amyotrophic lateral sclerosis.