However, with respect to LPS-stimulatedinflammation markers, associations remained significant for IL-8(β=0.075, P=0.01), MCP-1(β=0.097, P=0.003) and MMP2(β=0.083, P=0.008) with depressive symptomseverity, and for IL-6 (β=0.081, P=0.02),IL-8 (β=0.073, P=0.02), IL-10(β=0.083, P=0.02), IL-18(β=0.067, P=0.03), MCP-1(β=0.099, P=0.003), MMP2(β=0.124, P<0.001) and TNF-β(β=0.105, P=0.001) with anxiety symptomseverity. The gene discussed is IL18; the disease is Anxiety.