To assess whether associations were independent of lifestyle and healthfactors, significant markers were additionally adjusted for current smoking,alcohol intake, BMI and number of chronic diseases (results not tabulated).Associations turned to non-significant, except for IL-8, which was stillsignificantly associated with both remitted (OR=1.25,95%CI=1.04–1.49, P=0.02) and current(OR=1.28, 95%CI=1.08–1.52, P=0.005)depressive/anxiety disorders. The gene discussed is CXCL8; the disease is anxiety disorder.