Our results also showedassociations of cytokine production capacity with both depressive and anxietysymptoms, before and after adjustment for current smoking and alcohol intake.However, after further adjustment for BMI and number of chronic diseases,LPS-stimulated inflammation was more consistently associated with anxiety symptoms(index and IL-6, IL-8, IL-10, IL-18, MCP-1, MMP2, TNF-β) than with depressivesymptoms (IL-8, MCP-1, MMP2, but not the index). This evidence concerns the gene IL18 and Anxiety.