FAN1 and schizophrenia: Deletions in 15q13.2-13.3 have been implicated for SZ risk.59, 60 The disrupted genes include TRPM1, CHRFAM7A, MTMR10 and MTMR15, which are involved in DNA repair60, 61 and various neuropsychiatric disorders, including schizophrenia and addiction.62, 63, 64, 65 Overall, the structural variant in 15q13.2-13.3 is likely a risk factor for SZ.