CD4 and hepatitis B virus infection: This is similar to the findings of two recent studies from Zimbabwe and India.[25, 26] As a public health approach, this is another subset of patients (similar to HIV-infected persons having active TB disease, hepatitis B virus infection with severe chronic liver disease, being pregnant or breast feeding, being aged under five years, and living in a sero-discordant relationship) in whom ART should be recommended irrespective of CD4 count.