Several studies document decreased GSR-activity in animal models of myocardial infarction [30], ischemia and reperfusion [28] and in human patients with infarcted and reperfused hearts [29] which directed us to examine the interaction of GSR as a key enzyme of the glutathione redox system with mitoNEET-fostered anti-apoptotic effects. Here, GSR is linked to myocardial infarction.