P2RX7 and neoplasm: On the other hand, autophagy was reported to enhance production of ATP, which subsequently binds purinergic receptor P2RX7 in dendritic cells (DC), stimulates the recruitment of DC into the tumor bed, and finally leads to the immunogenic cell death (ICD) of tumor cells31, 32, suggesting the autophagy induced by Stel B might contribute to the antitumor efficacy.