HBEGF and Hydrocephalus: The orientation of β-gal distribution starting from the SVZ showed three primary streams in saggital sections: one in longitudinal trajectory to the OB (RMS), the second in radial localization especially in the HB-EGF homozygous animals with hydrocephalus, and the third in ventrolateral direction (Supplementary Fig. S5b) similar to the lateral cortical stream described during development6.