In Spain, Cotrina et al. [40] found that the HLA-DRB1 ∗1301 and DRB1 ∗1302 alleles are associated with infection resolution in acute hepatitis B. Li et al. [35] also showed that HLA-B ∗07 and DRB1 ∗13 may protect subjects from HBV infection. Here, HLA-B is linked to infection.