HFD caused adipocytes hypertrophy (the following data were calculated average areas: the CON mice, 6044.4 ± 359.1 μm2; the HF group, 10142.9 ± 428.1) and following treatment with AnK1 (6548.6 ± 214.7 μm2), AnK2 (6483.8 ± 319.8 μm2), AnK3 (5670.8 ± 281.6 μm2), Feno (6304.2 ± 316.9 μm2), or Metf (5873.7 ± 345.1 μm2) displayed less hypertrophy (Figure 4(a)). The gene discussed is ANK1; the disease is hydrops fetalis.