Using astrocyte and microglia cell models, Maxim et al. (2001) observed that HCMV stimulated the release of CCL2/MCP-1 and IL-8 in the supernatants of infected astrocytes, whereas infection of microglia cells led to an increased secretion of TNF-α, IL-6, CCL2/MCP-1, IL-8, CCL5/RANTES, and CCL3/MIP-1α. This evidence concerns the gene CXCL8 and infection.