In the in vitro cell model provided by human retinal pigment epithelial cells, Momma et al. (2003) observed, by means of RT-PCR and ELISA assays, that HCMV infection caused an upregulation of IL-8, whereas CCL2/MCP-1 and CCL7/MCP-3 levels were downregulated. The gene discussed is CCL2; the disease is cytomegalovirus infection.