Tau epitopes are found within Lewy bodies on immunostaining of PD postmortem brains (54), α-synuclein fibrils have been shown to induce polymerization of tau into hyperphosphorylated aggregates in vitro (55), and transgenic mice overexpressing α-synuclein have increased levels of hyperphosphorylated tau colocalizing with α-synuclein deposits (56). This evidence concerns the gene MAPT and Parkinson disease.