The most relevant factors associated with these different clinical behaviors of neuroblastomas are age at diagnosis, clinical stage, MYCN amplification, alterations of ploidy, numerical and structural chromosomal abnormalities, and histological degree of differentiation (Ambros et al., 1996; Bown et al., 1999; Janoueix-Lerosey et al., 2008; Molenaar et al., 2012; Cheung and Dyer, 2013; Pugh et al., 2013). Here, MYCN is linked to neuroblastoma.