Patients affected by episodic ataxia type 1, a form of episodic ataxia with myokymia (see below) caused by loss-of-function mutations in KCN1A (coding for Kv1.1 channel), often report abnormal EEGs, and several animal models carrying kcna1 gene defects show an increased susceptibility to seizures (Smart et al., 1998). The gene discussed is KCNA1; the disease is episodic ataxia type 1.