SCN1A and Dravet syndrome: In Dravet syndrome, as well as in other SCN1A-related seizure disorders, sodium channel blockers such as carbamazepine, lamotrigine, phenytoin are contraindicated as they may increase frequency and severity of seizures (Catterall, 2014; Miller and Sotero de Menezes, 2014; Schoonjans et al., 2015).