In leukaemia, although miR‐16 does not directly bind to the 3′‐UTR of the Wilms tumour protein 1 (WT1) mRNA, WT1 down‐regulation in response to miR‐16 significantly correlates with the development of acute myeloid leukaemia 39. The gene discussed is WT1; the disease is acute myeloid leukemia.