When comparing the strongest effect (OR = 0.3) of this new complotype on the risk of AMD with the odds ratios of the 38 individual loci described in the newest AMD GWAS36, we notice that the effect size is close to both the CFH (OR = 0.38) and the ARMS2 (OR = 2.81), albeit reverse, locus. Here, ARMS2 is linked to age-related macular degeneration.