TLR4 and meningococcal meningitis: In a following study conducted by the same group [37], not only an association between TLR4 +896 (D299G) SNP and meningococcal meningitis (MM) onset was reported, but also a strong correlation with the combined carriage of this TLR4 SNP and TLR2 +2477 (rs5743708) was observed in a large Dutch Caucasian cohort.