For instance, dyskeratosis congenita (DKC), a syndrome characterized by a classic triad of nail dysplasia, skin pigmentary changes, oral leukoplakia, and bone marrow failure, is associated with short telomeres and mutations in TCAB1 [25], dyskerin [26], NHP2 [26], and NOP10 [27]. Here, WRAP53 is linked to dyskeratosis congenita.