SOCS1 and familial pancreatic carcinoma: Pancreatic cancer cell migration, invasion and metastasis can be regulated by miR-155 via targeting 53-induced nuclear protein 1 (TP53INP1) [33,34] or by regulating the suppressor of cytokine signaling 1 (SOCS1) through the STAT3 signaling pathway [33,34,98,111].