AKT1 and familial pancreatic carcinoma: Although little information available regarding miR-208 expression and its role as an oncomiR in pancreatic cancer, a recent finding suggests that miR-208 regulates EMT by down-regulating E-cadherin and activating AKT/GSK-3β/snail signaling pathway, thereby promoting tumor cell invasion and metastasis of pancreatic cancer cells [38].