Cholesterol ester transfer protein (CETP), lipoprotein lipase (LPL) and hepatic lipase (LIPC) have all recently been reproducibly implicated as factoring into AMD risk (9, 35, 36) These proteins are central to proper handling and degradation of lipoproteins, further demonstrating the vital nature of lipid homeostasis in AMD prevention. Here, LIPC is linked to age-related macular degeneration.