Moreover, it was observed that both fractions and crude ethanol extract of MO inhibited acetylcholinesterase (AChE) of rats brain [17, 18] and also in vitro [9, 19, 20], but only two studies analyzed behavioral mechanism of action of MO extracts on scopolamine-induced memory impairment in rats [12, 18]. The gene discussed is ACHE; the disease is memory impairment.