In this regard, previous studies report conflicting results on chemerin levels in different diseases with an inflammatory component such as chronic pancreatitis (94.0 ng/mL) [40], T2DM individuals (179.0 ng/mL) [41], lipodystrophy (234.3 ng/mL) [42], and obesity without diabetes (590.08 ng/mL) [43]. Here, RARRES2 is linked to obesity due to melanocortin 4 receptor deficiency.