RARRES2 and obesity due to melanocortin 4 receptor deficiency: Chemerin levels were increased, except for the levels reported in rheumatoid arthritis (35.0 ng/mL) [44] (an inflammatory disease per se), although this can be explained based on treatment; however, other studies have suggested that chemerin may be the functional link between chronic inflammation and obesity-related T2DM and cardiovascular disease [45].