Ultimately, macrophage occurrence indicated by both CD68 and Iba-1 expression was also found in 28 out of 30 human biopsy samples from sporadic schwannomas, 9 out of 10 NF2-related schwannomas and in 4 out of 4 investigated Schwann cell tumors associated with schwannomatosis (Fig. 8b). The gene discussed is AIF1; the disease is schwannoma.