In order to experimentally test a cause and effect relationship between chronic inflammation and schwannoma growth, we administered medium-dose aspirin (5 mg per kg equates to a dose of approximately 375 mg for humans) as commonly used anti-inflammatory drug to P0-Cre;Nefh-Cre;Nf2fl/+ mice after tumor induction by nerve crush injury (Fig. 9a). Here, NEFH is linked to neoplasm.