Three-group comparison across APOBEC3B copy number for macrophages M2 fractions was not significant with A3Bdel/del, A3Bdel/wt, and A3Bwt/wt breast cancers with mean fractions of 0.179, 0.197 and 0.207, respectively (Additional file 1: Table S6). This evidence concerns the gene APOBEC3B and breast cancer.