Furthermore, Chang et al. [104] showed that the ratio between JEV sfRNA and genomic RNA (sfRNA:gRNA) was increased in a later stage (5 dpi) compared with acute JEV (RP-9 strain) infection (48 hpi) in BHK-21 and C6/36 cell lines (IFN-incompetent cells). This evidence concerns the gene IFNA1 and infection.