IFNA1 and infection: Regarding this subject, Bidet at al. [93] have shown that the sfRNA generated during DENV-2 (New Guinea C strain) infection of a hepatocarcinoma cell line (Huh7) was able to antagonize host RNA-binding proteins (G3BP1, G3BP2 and CAPRIN1) and regulate ISGs expression, consequently avoiding the antiviral IFN-mediated response.