L1CAM and cancer: Noteworthy, L1CAM promoter methylation was found to be significantly lower in FIGO stage IIIc (median value: 12.18; Q1-Q3: 3.83-28.52) compared to stage I-II cancers (median value 33.35; Q1-Q3:21.58-44.31; p = 0.009), in grade 3 (median value: 23.66; Q1-Q3: 9.61-35.57) compared to grade 1 and 2 cancers (median value: 32.37; Q1-Q3: 21.58-44.31; p = 0.05) and in cancers with metastatic lymph nodes (median value: 12.18; Q1-Q3: 3.83-28.52) in comparison with negative lymph node status nodes (median value: 35.81; Q1-Q3: 21.70-45.77; p = 0.022).