In addition to the effects on Notch-1 leukemia cell lines, the growth of other cancers, such as pancreatic and biliary cancer cell lines which produce CA19-9, were effectively suppressed by F50-Liposome-cisplatin, indicating the potential applicability of this nanoparticle technology for the treatment of different types of cancer (data not shown) [11]. The gene discussed is NOTCH1; the disease is leukemia.