In this paper, we report the screening of α-amyrins as natural potent anti-cancer as well as anti-inflammatory compounds derived from Cordia species seed for dual inhibition of COX2 and 5-LOX enzymes by molecular docking and evaluate its drug likeness and toxicity, to study the binding pattern and characteristics of the molecule for application as a novel drug in treatment of inflammatory diseases. Here, PTGS2 is linked to cancer.