Gene-expression analysis in adenocarcinomas based on microarray data showed that VRK1 was correlated with members of the mitotic cell-cycle gene network, including CENP-A, CENP-K, CENP-N, CENP-Q, Bub1, BubR1, SMC2, and CAP-G (76). Here, SMC2 is linked to adenocarcinoma.