BRCA1 and neoplasm: Thus, the CD44+/24–/low expression profile paralleled a BRCA1 defect though the general predominance exhibited tumor sub-type specificity with normal-like tumor forming cells (MDA-MB-436 and MDA-MB-231) possessing more CD44+/24–/low cells than the basal-like tumor inducing cell lines (HCC1937 and HCC1937/wt BRCA1).