To assess whether MTDH and VDAC1 are clinically correlated with miR-320a expression, we examined their expression in 18 paired fresh tissue samples where miR-320a was underexpressed in breast cancer more than 2-fold in comparison to normal adjacent breast tissues by western blot (MTDH and VDAC1) and PCR (miR-320a). This evidence concerns the gene VDAC1 and breast carcinoma.