A second case of downregulation of Panx1 in cancer tissues was reported in a review paper by Schalper et al. [3] where immunohistochemistry of normal human gallbladder and gallbladder adenocarcinoma with anti- Panx1 antibodies indicated a lower expression of Panx1 in tumour cells. The gene discussed is PANX1; the disease is gallbladder adenocarcinoma.