SLC26A3 and hyperaldosteronism: But NHE3 mRNA expression levels were not upregulated in the jejunum of NBCe1 KO compared to WT mice (Fig. 8), a finding that is in agreement with our previous observation that hyperaldosteronism induced by low-salt diet (Riederer, unpublished observations) or by Slc26a3 deficiency [44] had a strong effect on colonic, but not on jejunal NHE3 expression levels.