In addition, a trend of inverse correlation between RanGAP1 and miR-1301 levels was observed in CML patients (coefficient of determination, R2 = 0.826; Pearson product-moment correlation coefficient, R = 0.922; p = 0.078) (Fig 5C and S2 Table). The gene discussed is RANGAP1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.