IGHE and Alzheimer disease: IgE-reactivity to the different rMala s allergens varied between 2–30% among the AD patients, with higher percentages for each of the allergens in the severe AD group (Table 2) and with 4–67% IgE-reactivity among the AD patients ImmunoCAPTM or immunoblot positive to the M. sympodialis extract (S2 Table).