AFP and neoplasm: The tumor size, tumor node metastasis (TNM) stage, AFP level, presence or absence of hepatitis B surface antigen (HbsAg), and differentiation degree were all related to FOXO6 expression level (P <0.05), but no significant associations between FOXO6 expression and age, sex, tumor number, violation of portal vein system, and lymph node metastasis were detected (all P >0.05) (Table 4).