DUSP1 and neoplasm: These initial studies revealed a higher DUSP1 expression in a range of human epithelial tumors including prostate, colon, and bladder, however, the expression of DUSP1 in tumors decreased progressively with a higher histological grade 15, 16, 17.Some studies also suggested that DUSP1 was involved in tumor therapy efficiency 18, 19, 20, 21, 22.