APOA5 rs3135506, which predisposes to hypertriglyceridemia in homozygous form [12], was 1.8–fold more frequent in the affected individuals of the FCH families than in the general population (minor allele frequency [MAF] in affected FCH individuals = 0.11, MAF in population = 0.062). The gene discussed is APOA5; the disease is hypertriglyceridemia.